background: newcastle disease virus (ndv) is the causativeagent of the newcastle disease (nd), a highly contagiousdisease in birds that causes significant economic losses to thepoultry industry worldwide. nd is endemic in iran and outbreaksare reported regularly in commercial poultry flocks and differentspecies of birds. objectives:the current study was carried outto characterize ndv based on p...

background and aims: crimean-congo hemorrhagic fever (cchf) is a fatal viral disease that occurs in approximately 30 countries. it has the most extensive geographic range among the tick-borne viruses that affect human health. cchf viruses have a tripartite rna genome consisting of large (l), medium (m) and small (s) segments. this study was undertaken to determine the genetic relationship of cc...

background and aims: infectious bronchitis virus (ibv) is the etiological agent of infectious bronchitis (ib), which is an acute and highly contagious disease of the respiratory and sometimes the urogenital tracts of chickens. in iran, the disease has been identified in chicken flocks with serological and virus isolation methods. gene 3c (e) encode envelop (small membrane) protein. for envelope...

background and aims: newcastle disease virus (ndv) infection have been established in at least 241species of birds representing 27 of the 50 orders of the class.ndv isolate were obtained from infected ostrich flock during the outbreaks of nd in iran 2012. the f gene fragment which codes the main functional region of the f protein was obtained by rt-pcr and sequenced. methods: from the pathotype...

background: canine distemper (cd) is a lethal systemicdisease affecting a wide variety of terrestrial carnivores.objectives: this study was performed to survey epidemiologicaland molecular characteristics of the canine distemper virus(cdv) strains circulating in iran. methods: in this study, 19cdv-suspected unvaccinated dogs from northeast and center ofiran were analyzed for presence of cdv nuc...

abstract background and aims: newcastle disease (nd) is a highly contagious disease that affects many species of birds and causes significant economic losses to the poultry industry worldwide and the pathogenicity of newcastle disease virus (ndv) strains varies with different virulence. we aim to detect lentogenic (low virulence) nd virus (nd/ir 2010) using sentinel birds and molecular detectio...

background and aims: avian influenza (ai) h9n2 subtype was first reported to infect turkeys in the united states in 1966 and has been panzootic in eurasia. in iran, the h9n2 virus was first isolated from broiler chickens in 1998 in ghazvin province and it is the most prevalent subtype of influenza virus in poultry industry in iran at the present time. materials and methods: in this study, we se...

background and aims: avian influenza (ai) h9n2 subtype was first reported to infect turkeys in the united states in 1966 and has been panzootic in europe and asia. the impact of avian influenza caused by h9n2 viruses in iran is now significantly more severe than in previous years. methods: sequence analysis and phylogenetic study of the complete coding region polymerase a (pa) gene of h9n2 subt...

conclusions genotypes 1 and 4 demonstrated remarkable similarity in terms of genome sequences and proteins, but surprisingly, in terms of the preferred codons for gene expression, they showed the greatest difference. more studies are therefore needed to confirm the results and select the best approach for treatment of these genotypes based on their codon usage properties. results the six genoty...

the archaeological evidence suggests that iran has been one of the first origins of sheep domestication in the world. this study aims to investigate the genetic diversity of indigenous iranian sheep breeds using mitochondrial dna (mtdna) and to explore the evolutionary history of sheep domestication in iran. single nucleotide polymorphism (snp) markers in the control region of mtdna were used t...